Research Fellow (Tenure-track), Center for Cognition and Sociality, IBS, Daejeon, Korea
Education
PhD, Seoul National University (2004)
Major Experience
1997Sogang University
2004PhD. Department of Physiology, Seoul National University College of Medicine
2004-2010Postdoctoral Fellow, Department of Neuroscience, Johns Hopkins University School of Medicine
2010-2012Research Associate, Department of Neuroscience, Johns Hopkins University School of Medicine
2012-2015Assistant Professor, Department of Physiology, Jeju National University School of Medicine
2015-Research Fellow (Tenure-track), Center for Cognition and Sociality, IBS
Honors
The distinguished Scientist Support program funded by Jeju National University (2014)
Major Publication
mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE. Neuron 57(6): 858-871, 2008
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron 59(1): 70-83 (*equal contribution), 2008
Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons. Nature Neuroscience 13(9): 1090-1097,2010
Homeostatic scaling requires group I mGluR activation mediated by Homer1a. Neuron 68:1128-1142 (*equal contribution), 2010
Preso1 dynamically regulates group I metabotropic glutamate receptors. Nature Neuroscience 15(6):836-844, 2012
Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. Science Translational medicine 5(201):201ra120, 2013
A Prolyl-isomerase Mediates Dopamine-dependent Plasticity and Cocaine Motor Sensitization. Cell 154(3):637-650 (*equal contribution), 2013
Long-term Synaptic Plasticity: Circuit Perturbation and Stabilization. Korean Journal of Physiology and Pharmacology 18(6):457-460
mGluR1 receptor mediates homeostatic control of intrinsic excitability through Ih in cerebellar Purkinje cells. J Neurophysiol 115: 2446-2455, 201
Protein Arginine Methylation Facilitates KCNQ Channel-PIP2 Interaction Leading to Seizure Suppression. eLife 2016;5:e17159, 2016
Real-Time Imaging Reveals Properties of Glutamate-Induced Arc.Arg3.1 Translation in Neuronal Dendrites. Neuron 91: 561-573, 2016