기초과학연구원 의생명수학그룹
In this talk, we discuss the paper, “A frequency-amplitude coordinator and its optimal energy consumption for biological oscillators”, by Bo-Wei Qin et. al., Nature Communications, 2021. Zoom : https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09 Abstract Biorhythm …
Abstract: There has been an increased use of scoring systems in clinical settings for the purpose of assessing risks in a convenient manner that provides important evidence for decision making. …
In this talk, we discuss the paper : "Noise robustness and metabolic load determine the principles of central dogma regulation" by Teresa W. Lo et al, Sci. Adv, https://doi.org/10.1126/sciadv.ado3095. Zoom: …
Abstravt: Latent space dynamics identification (LaSDI) is an interpretable data-driven framework that follows three distinct steps, i.e., compression, dynamics identification, and prediction. Compression allows high-dimensional data to be reduced so …
In this talk, we discuss the paper : "Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment" …
Abstract: We propose a universal method for data-driven modeling of complex nonlinear dynamics from time-resolved snapshot data without prior knowledge. Complex nonlinear dynamics govern many fields of science and engineering. …
Abstract: The effect of malaria on the developing world is devastating. Each year there are more than 200 million cases and over 400,000 deaths, with children under the age of …
In this talk, we discuss the paper "Next generation reservoir computing", by Gauthier, et.al, Nat. Comm., 2021. Abstract : Reservoir computing is a best-in-class machine learning algorithm for processing information …
In this talk, we discuss the paper "SVD-AE: An asymmetric autoencoder with SVD regularization for multivariate time series anomaly detection" by Yueyue Yao, et.al., Neural Networks, 2024. Abstract Anomaly detection in …
Abstract: Malignant gliomas are highly invasive brain tumors. Recent attention has focused on their capacity for network-driven invasion, whereby mitotic events can be followed by the migration of nuclei along …
Title: Theoretical studies on biological oscillations by using waveform data and mathematical models Abstract: Temporal waveforms of biological oscillations are of various shapes. In our research, we have explored the functional implications of these waveform shapes. In particular, we theoretically showed that the period of circadian clocks is proportional to the waveform distortion from sinusoidal wave. It suggests that the circadian period can be stable against temperature changes only if the waveform becomes more distorted at higher temperatures. In this talk, I will explain my past research and discuss my future plans. Reference: Shingo Gibo, Gen Kurosawa, Non-sinusoidal Waveform in Temperature Compensated Circadian Oscillations, Biophysical Journal 116 (4) 741-751 (2019). doi: 10.1016/j.bpj.2018.12.022 Shingo Gibo, Gen Kurosawa, Theoretical study on the …
Abstract: Circadian clocks in cells and humans are heterogeneous in period and phase. This heterogeneity can be exploited not only to gain insight into the molecular basis of circadian rhythms, …