Mathematics
Krešimir Josić
Department of Mathematics, U of Houston, USACollaborative works
Long-range temporal coordination of gene expression in spatially extended synthetic microbial consortia, Nature Chem Biol (2019)
Bayesian inference of distributed time delay in transcriptional and translational regulation, Bioinformatics (2019)
The relationship between deterministic and stochastic quasi-steady-state approximation, BMC Syst Biol (2015)
Emergent genetic oscillations in a synthetic microbial consortium, Science (2015)
The Validity of Quasi-Steady-State Approximations in Discrete Stochastic Simulations, Biophy J (2014)
Molecular mechanisms that regulate the coupled period of the mammalian circadian clock, Biophy J (2014)
John Tyson
Department of Biological Sciences, Virginia Tech, USACollaborative works
A systems- driven experimental approach reveals the complex regulatory distribution of p53 by circadian factors, PNAS (2016)
Misuse of the Michaelis-Menten rate law for protein-interaction networks and its remedy, PLoS Comput Biol (2020)
Sookkyung Lim
Mathematical Sciences, University of Cincinnati, USACollaborative works
Modeling reveals a key mechanism for light-dependent phase shifts of Neurospora circadian rhythms, Biophy J (2018)
Boseung Choi
Department of National Statistics, Korea University Sejong, Republic of KoreaCollaborative works
Bayesian inference of distributed time delay in transcriptional and translational regulation, Bioinformatics (2019)
Beyond Michaelis-Menten: Accurate and efficient estimation of enzyme kinetic parameters, Scientific Report (2017)
Grzegorz Rempala
Division of Biostatistics and Mathematical Biosciences Institute, The Ohio State University, USACollaborative works
Reduction for stochastic reaction network with multi-scale conservation, SIAM Multiscale Model Simul (2017)
Beyond Michaelis-Menten: Accurate and efficient estimation of enzyme kinetic parameters, Scientific Report (2017)
Eduardo D. Sontag
Departments of Electrical and Computer Engineering and of Bioengineering, Northeastern University, USACollaborative works
Derivation of stationary distributions of biochemical reaction networks via structure transformation (Submitted)
Reduction of Multiscale Stochastic Biochemical Reaction Networks using Exact Moment Derivation, PLoS Comput Biol (2017)
Victoria Booth
Department of Mathematics, U of Michigan, USACollaborative works
Personalized sleep-wake patterns aligned with circadian rhythm relieve daytime sleepiness (Submitted)
Daniel Forger
Department of Mathematics, U of Michigan, USACollaborative works
A Period2 Phosphoswitch Regulates and Compensates Circadian Period, Molecular Cell (2015)
Modeling and Validating Chronic Pharmacological Manipulation of Circadian Rhythms, CPT:PSP (2013)
A Mechanism for Robust Circadian Timekeeping via stoichiometric balance, Mol Syst Biol (2012)
On the Existence and Uniqueness of Biological Clock Models Matching Experimental Data, SIAM J APPL MATH (2012)
Jonathan Tyler
Department of Mathematics, U of Michigan, USACollaborative works
Inferring causality in biological oscillators (Submitted)
Jinsu Kim
Department of Mathematics, University of California, Irvine, USACollaborative works
Derivation of stationary distributions of biochemical reaction networks via structure transformation (Submitted)
Eder Zavala
Institute of Metabolism and Systems Research MRC Skills Development Fellow, University of BirminghamCollaborative works
Wearable technology and systems modeling for personalized chronotherapy, Curr. Opin. Syst. Biol. (2020)
Biology
Choogon Lee
Dept. of Biomedical Sciences & Neuroscience, Florida State U., USACollaborative works
Wake-sleep cycles are severely disrupted by diseases affecting cytoplasmic homeostasis, PNAS (2020)
Stability of the circadian system requires a robust degradation of PERIOD, Current Biol (2017)
A tunable artificial circadian clock in clock-defective mice, Nature Commun (2015)
David Virshup
Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, SingaporeCollaborative works
Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch, PNAS (2020)
CK1 protein kinases prime the PER2 circadian phosphoswitch, PNAS (2018)
A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period, Molecular Cell (2015)
Carla Finkielstein
Department of Biological Sciences, Virginia Tech, USACollaborative works
A systems biology approach identifies hidden regulatory connections between the circadian and cell-cycle checkpoints, Front Physiol (2020)
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein MDM2, Science Signal (2018)
A systems- driven experimental approach reveals the complex regulatory distribution of p53 by circadian factors, PNAS (2016)
Christian I. Hong
Pharmacology and Systems Physiology, U of Cincinnati, USACollaborative works
Modeling reveals a key mechanism for light-dependent phase shifts of Neurospora circadian rhythms, Biophy J (2018)
Matthew Bennett
Department of Biosciences, Rice University, USACollaborative works
Long-range temporal coordination of gene expression in spatially extended synthetic microbial consortia, Nature Chem Biol (2019)
The relationship between deterministic and stochastic quasi-steady-state approximation, BMC Syst Biol (2015)
Emergent genetic oscillations in a synthetic microbial consortium, Science (2015)
The validity of quasi-steady-state approximations in discrete stochastic simulations, Biophy J (2014)
Molecular mechanisms that regulate the coupled period of the mammalian circadian clock, Biophy J (2014)
Dae-Jin Yun
Department of Biomedical Science & Engineering, Konkuk University, Republic of KoreaCollaborative works
Rheostatic control of ABA signaling through HOS15-mediated OST1 degradation, Molecular Plant (2019)
Woe Yeon Kim
Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Republic of KoreaCollaborative works
Rheostatic control of ABA signaling through HOS15-mediated OST1 degradation, Molecular Plant (2019)
Eun Young Kim
Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Republic of KoreaCollaborative works
Model-driven experimental approach reveals the molecular differences in pacemaker neurons in Drosophila circadian clock (To be submitted)
Sara Aton
Department of Molecular, Cellular, and Developmental Biology, U of MichiganCollaborative works
Possible “non-clock” functions of circadian clock genes – Potential roles in sleep, stress, and memory (In press)
Matias D. Zurbriggen
Institute of Synthetic Biology and CEPLAS, Heinrich Heine University Düsseldorf, GermanyCollaborative works
Possible “non-clock” functions of circadian clock genes – Potential roles in sleep, stress, and memory (In press)
Robbert Havekes
Department of Biology, University of Pennsylvania, USAGroningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, The Netherlands
Collaborative works
Possible “non-clock” functions of circadian clock genes – Potential roles in sleep, stress, and memory (In press)
Medicine
Eun Yeon Joo
Department of Neurology, Neuroscience Center, Samsung Medical Center, Republic of KoreaCollaborative works
Personalized sleep-wake patterns aligned with circadian rhythm relieve daytime sleepiness (Submitted)
Jeong Whun Kim
Department of Otorhinolaryngology, Seoul National University Bundang Hospital, Republic of KoreaCollaborative works
Combined unsupervised-supervised machine learning for phenotyping complex diseases with its application to obstructive sleep apnea, Scientific Reports (2021)
Young Il Koh
Department of Internal Medicine, Seoul National University Hospital, Republic of KoreaCollaborative works
Cancer chronotherapy
Pharmacology
Cheng Chang
Clinical Pharmacology, Pfizer Global Product Development, Pfizer Inc, USACollaborative works
Systems approach reveals photosensitivity and PER2 level as determinants of clock modulator efficacy, Mol Syst Biol (2019)
Modeling and Validating Chronic Pharmacological Manipulation of Circadian Rhythms, CPT:PSP (2013)
Francois Gaudreault
Clinical Pharmacology and Pharmacometrics, Biogen Inc, USACollaborative works
Systems approach reveals photosensitivity and PER2 level as determinants of clock modulator efficacy, Mol Syst Biol (2019)
Hwi‐yeol Yun
College of Pharmacy, Chungnam National University, Republic of KoreaCollaborative works
Beyond the Michaelis-Menten: Prediction of in vivo clearance for drugs with low KM, Clin Transl Sci (2020)
Sang Kyum Kim
College of Pharmacy, Chungnam National University, Republic of KoreaCollaborative works
Beyond the Michaelis-Menten: Prediction of in vivo clearance for drugs with low KM, Clin Transl Sci (2020)
Jungwoo Chae
College of Pharmacy, Chungnam National University, Republic of KoreaCollaborative works
Investigation of CYP enzyme induction with tQSSA