기초과학연구원 의생명수학그룹
In this talk, we discuss the paper "Accurate predictions on small data with a tabular foundation model" by Noah Hollmann et al., Nature (2025). Abstract Tabular data, spreadsheets organized in rows and columns, are ubiquitous across scientific fields, from biomedicine to particle physics to economics and climate science1,2. The fundamental prediction task of filling in …
In this talk, we discuss the paper, "Entrainment and multi-stability of the p53 oscillator in human cells" by Alba Jiménez et al., Cell Systems, 2024. Abstract The tumor suppressor p53 responds to cellular stress and activates transcription programs critical for regulating cell fate. DNA damage triggers oscillations in p53 levels with a robust period. Guided by …
In this talk, we discuss the paper "Identifying key drivers in a stochastic dynamical system through estimation of transfer entropy between univariate and multivariate time series" by Julian Lee, Physical Review E, 2025. Abstract Transfer entropy (TE) is a widely used tool for quantifying causal relationships in stochastic dynamical systems. Traditionally, TE and its conditional …
In this talk, we discuss the paper "Boolean modelling as a logic-based dynamic approach in systems medicine" by Ahmed Abdelmonem Hemedan et al., Computational and Structural biotechnology journal (2022). Abstract Molecular mechanisms of health and disease are often represented as systems biology diagrams, and the coverage of such representation constantly increases. These static diagrams can …
Abstract Many natural systems exhibit oscillations that show sizeable fluctuations in frequency and amplitude. This variability can arise from a wide variety of physical mechanisms. Phase descriptions that work for deterministic oscillators have a limited applicability for stochastic oscillators. In my talk I review attempts to generalize the phase concept to stochastic oscillations, specifically, the …
Abstract Spontaneous rhythmic oscillations are widely observed in real-world systems. Synchronized rhythmic oscillations often provide important functions for biological or engineered systems. One of the useful theoretical methods for analyzing rhythmic oscillations is the phase reduction theory for weakly perturbed limit-cycle oscillators, which systematically gives a low-dimensional description of the oscillatory dynamics using only the …
