We will discuss about “A spatio-temporal model to reveal oscillator phenotypes in molecular clocks: Parameter estimation elucidates circadian gene transcription dynamics in single-cells”, Unosson et al., bioRxiv, 2021 We propose a stochastic distributed delay model together with a Markov random field prior and a measurement model for bioluminescence-reporting to analyse spatiotemporal gene expression in intact …

We will discuss about “Balanced truncation for model reduction of biological oscillators”, Padoan et al., Biological Cybernetics, 2021 Model reduction is a central problem in mathematical biology. Reduced order models enable modeling of a biological system at different levels of complexity and the quantitative analysis of its properties, like sensitivity to parameter variations and resilience …