기초과학연구원 의생명수학그룹
Abstract: Inference method for a stochastic target-mediated drug disposition model via ABC-MCMC In this study, we discuss model robustness. Model robustness is consistent performance over variations of parameters. We formulate …
Abstract: Systems biology seeks to build quantitative predictive models of biological system behavior. Biological systems, such as the mammalian immune system, operate across multiple spatiotemporal scales with a myriad of …
This talk will be presented online. Zoom link: 709 120 4849 (pw: 1234) Abstract: Homeostasis is a recurring theme in biology that ensures that regulated variables robustly adapt to environmental …
We will discuss about “Stochastic reaction networks in dynamic compartment populations”, Duso and Zechner, PNAS, 2020 Abstract: Compartmentalization of biochemical processes underlies all biological systems, from the organelle to the …
We will discuss about “Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation”, Li et. al., Cell Systems, 2018 Abstract Gene regulation is a complex non-equilibrium process. Here, …
We will discuss about “TimeCycle: Topology Inspired MEthod for the Detection of Cycling Transcripts in Circadian Time-Series Data”, Ness-Cohn and Braun, Bioinformatics, 2021 Abstract Motivation: The circadian rhythm drives the …
Abstract: Most organisms exhibit various endogenous oscillating behaviors, which provides crucial information about how the internal biochemical processes are connected and regulated. Along with physical experiments, studying such periodicity of …
We will discuss about "Cellular signaling beyond the Wiener-Kolmogorov limit", Weisenberger et al., bioRxiv, 2021 Abstract: Accurate propagation of signals through stochastic biochemical networks involves significant expenditure of cellular resources. …
This talk will be presented online. Zoom link: 709 120 4849 (pw: 1234) Abstract: Our current approach to cancer treatment has been largely driven by finding molecular targets, those patients …
We will discuss about "Machine learning of stochastic gene network phenotypes", Park et al., bioRxiv, 2019 Abstract: A recurrent challenge in biology is the development of predictive quantitative models because …
CANCELED due to unexpected circumstances This talk will be presented online. Zoom link: 709 120 4849 (pw: 1234) Abstract: While the presence of immune cells within solid tumours was initially …
We will discuss about “Nonlinear delay differential equations and their application to modeling biological network motifs”, Glass et al., Nature Communications, 2021 Abstract: Biological regulatory systems, such as cell signaling …