Universal biology in adaptation and evolution: dimensional reduction, and fluctuation-response relationship
ZOOM ID: 997 8258 4700 (Biomedical Mathematics Online Colloquium) (pw: 1234)This talk will be presented online. Zoom link: 997 8258 4700 (pw: 1234) Abstract: A macroscopic theory for cellular states with steady-growth is presented, based on consistency between cellular growth and molecular replication, together with robustness of phenotypes against perturbations. Adaptive changes in high-dimensional phenotypes are shown to be restricted within a low-dimensional slow manifold, …