기초과학연구원 의생명수학그룹
Abstract: Multi-omics technologies, and in particular those with single-cell and spatial resolution, provide unique opportunities to study the deregulation of intra- and inter-cellular signaling processes in disease. I will present …
We will discuss about “Single-sample landscape entropy reveals the imminent phase transition during disease progression”, Liu R, Chen P, Chen L., Bioinformatics. 2020 Mar 1;36(5):1522-1532. Abstract Motivation: The time evolution …
Abstract The standard approach to problem-solving in physics consists of identifying state variables of the system, setting differential equations governing the state evolution, and solving the obtained. The behavior of …
We will discuss about “The effect of microRNA on protein variability and gene expression fidelity”, Hilfinger, Andreas, and Raymond Fan., Biophysical journal 122.3 (2023): 537a. Abstract Small regulatory RNA molecules such …
Abstract: Many questions in everyday life as well as in research are causal in nature: How would the climate change if we lower train prices or will my headache go …
Fast and accurate predictions for complex physical dynamics are a big challenge across various applications. Real-time prediction on resource-constrained hardware is even more crucial in the real-world problems. The deep …
Abstract: We will present a new approach to develop a data-driven, learning-based framework for predicting outcomes of biophysical systems and for discovering hidden mechanisms and pathways from noisy data. We …
We will discuss about “The ups and downs of biological oscillators: A comparison of time-delayed negative feedback mechanisms”,Rombouts, Jan, Sarah Verplaetse, and Lendert Gelens., bioRxiv (2023) Abstract Many biochemical oscillators …
We will discuss about “Comparison of transformations for single-cell RNA-seq data”,Ahlmann-Eltze, Constantin, and Wolfgang Huber, Nature Methods (2023): 1-8. Abstract The count table, a numeric matrix of genes × cells, is the …
We will discuss about “Improving gene regulatory network inference and assessment: The importance of using network structure”, Escorcia-Rodríguez, Juan M., et al., bioRxiv (2023): 2023-01. Abstract Gene regulatory networks are graph …
Abstract: The well-known two-process model of sleep regulation makes accurate predictions of sleep timing and duration, as well as neurobehavioral performance, for a variety of acute sleep deprivation and nap …
High accuracy of major biological processes relies on the ability of the participating enzymatic molecules to preferentially select the correct substrate from a pool of chemically similar substrates by activating …