• Learning stable and predictive structures in kinetic systems

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Learning stable and predictive structures in kinetic systems", Niklas Pfister , Stefan Bauer, and Jonas Peters. PNAS, 2019 Abstract: Learning kinetic systems from data is one of the core challenges in many fields. Identifying stable models is essential for the generalization capabilities of data-driven inference. We introduce a computationally efficient framework,

  • Neural Ordinary Differential Equations

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Neural Ordinary Differential Equations", Chen, Ricky TQ, et al., Advances in neural information processing systems 31 (2018). Abstract: We introduce a new family of deep neural network models. Instead of specifying a discrete sequence of hidden layers, we parameterize the derivative of the hidden state using a neural network. The output

  • Molecular convolutional neural networks with DNA regulatory circuits

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Molecular convolutional neural networks with DNA regulatory circuits", Pei, Hao, et al., Nature Machine Intelligence (2022): 1-11. Abstract: Complex biomolecular circuits enabled cells with intelligent behaviour to survive before neural brains evolved. Since DNA computing was first demonstrated in the mid-1990s, synthetic DNA circuits in liquid phase have been developed as

  • Circadian Interventions in Shift Workers

    This talk will be given online (If you want to join, please send me an email to jaekkim@ibs.re.kr) Abstract Coupling Math with User-Centric Design Shift workers experience profound circadian disruption due to the nature of their work, which often has them on-the-clock at times when their internal clock is sending a strong, sleep-promoting signal. Mathematical

  • Inferring Regulatory Networks from Expression Data Using Tree-Based Methods

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Inferring Regulatory Networks from Expression Data Using Tree-Based Methods," Huynh-Thu et al., PLoS ONE (2010). Abstract: One of the pressing open problems of computational systems biology is the elucidation of the topology of genetic regulatory networks (GRNs) using high throughput genomic data, in particular microarray gene expression data. The Dialogue for

  • Cell signaling in 2D vs. 3D

    ZOOM ID: 997 8258 4700 (Biomedical Mathematics Online Colloquium) (pw: 1234)

    Abstract: The activation of Ras depends upon the translocation of its guanine nucleotide exchange factor, Sos, to the plasma membrane. Moreover, artificially inducing Sos to translocate to the plasma membrane is sufficient to bring about Ras activation and activation of Ras’s targets. There are many other examples of signaling proteins that must translocate to the

  • Hidden Markov models for monitoring circadian rhythmicity in telemetric activity data

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Hidden Markov models for monitoring circadian rhythmicity in telemetric activity data", Huang, Qi, Journal of The Royal Society Interface 15.139 (2018): 20170885. Abstract: Wearable computing devices allow collection of densely sampled real-time information on movement enabling researchers and medical experts to obtain objective and non-obtrusive records of actual activity of a

  • Physics-informed neural networks for PDE-constrained optimization and control

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Physics-informed neural networks for PDE-constrained optimization and control", Barry-Straume, Jostein, et al., arXiv preprint arXiv:2205.03377 (2022). Abstract: A fundamental problem of science is designing optimal control policies that manipulate a given environment into producing a desired outcome. Control PhysicsInformed Neural Networks simultaneously solve a given system state, and its respective optimal

  • STEM Initiatives for Agricultural 4.0 and Beyond

    This talk will be given online. Abstract: The establishment of UN Sustainable Development Goals (SDG) has led to widespread initiative in STEM learning and research in realising these goals. Here, we will look at some of the works that use control engineering approaches for smart farming (also known as Agriculture 4.0) applications that addresses UN

  • Design frameworks for engineering efficient cell factory performance within host and industrial constraints

    This talk will be given online. Abstract: Synthetic biology and microbial biotechnology offer sustainable routes to the manufacture of commodity and high value chemicals from agricultural by-products instead of petrochemical feedstocks. However, engineered gene circuits and metabolic pathways both co-opt the cell’s gene expression machinery for protein/enzyme production and divert metabolic flux away from key

  • Cell clustering for spatial transcriptomics data with graph neural networks

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    We will discuss about "Cell clustering for spatial transcriptomics data with graph neural networks", Li, J., Chen, S., Pan, X. et al., Nat Comput Sci 2, 399–408 (2022) Abstract: Spatial transcriptomics data can provide high-throughput gene expression profiling and the spatial structure of tissues simultaneously. Most studies have relied on only the gene expression information but

  • Causal Inference – basics and examples

    B378 Seminar room, IBS 55 Expo-ro Yuseong-gu, Daejeon, Korea, Republic of

    Abstract: In real world, people are interested in causality rather than association. For example, pharmaceutical companies want to know effectiveness of their new drugs against diseases. South Korea Government officials are concerned about the effects of recent regulation with respect to an electric car subsidy from United States. Due to this reason, causal inference has

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IBS Biomedical Mathematics Group (BIMAG)
Institute for Basic Science (IBS)
55 Expo-ro Yuseong-gu Daejeon 34126 South Korea
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