기초과학연구원 의생명수학그룹
Abstract: Cell-to-cell variability in gene expression exists even in a homogeneous population of cells. Dissecting such cellular heterogeneity within a biological system is a prerequisite for understanding how a biological …
Abstract: Through the past decades, electrophysiological experiments have revealed that extracellular electrical potential of brain show diverse rhythmic activity. Called ‘Local Field Potential(LFP)’, those rhythmic activities are thought to reflect …
Abstract: The Downing lab investigates the intricate biophysical interactions between cells and their environment, elucidating their role in modulating adult cell behavior and phenotypic transitions via epigenetic regulation of gene …
I present time delay estimation problems in astronomy as a part of time delay cosmography to infer the Hubble constant, the current expansion rate of the Universe. Time delay cosmography …
Presentor(s) Mentor Talk title Jaehun Jeong Gyuyoung Hwang Analyzing coupled SCN cell frequencies of mammals for multi-step transcriptional model Hyunsuk Choo, Yonghee Lee Seok Joo Chae Development of a …
Abstract: A system of ordinary differential equations (ODEs) is one of the most widely used tools to describe a deterministic dynamical system. In general, such ODEs involve nonlinear equations, which make analysis of dynamical systems difficult. In this talk, we introduce Koopman theory, which offers a linear representation – not an approximation – of nonlinear dynamics. In particular, we present a data-driven algorithm to find such a linear representation
Abstract: Wearable biosensors measure physiological variables with high temporal resolution over multiple days and are increasingly employed in clinical settings, such as continuous glucose monitoring in diabetes care. Such datasets …
The talk will be hybrid, participants may join via Zoom with the following link: https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09
Title: Theoretical studies on biological oscillations by using waveform data and mathematical models Abstract: Temporal waveforms of biological oscillations are of various shapes. In our research, we have explored the functional implications of these waveform shapes. In particular, we theoretically showed that the period of circadian clocks is proportional to the waveform distortion from sinusoidal wave. It suggests that the circadian period can be stable against temperature changes only if the waveform becomes more distorted at higher temperatures. In this talk, I will explain my past research and discuss my future plans. Reference: Shingo Gibo, Gen Kurosawa, Non-sinusoidal Waveform in Temperature Compensated Circadian Oscillations, Biophysical Journal 116 (4) 741-751 (2019). doi: 10.1016/j.bpj.2018.12.022 Shingo Gibo, Gen Kurosawa, Theoretical study on the …
In this talk, we discuss the paper : “Solving Inverse Problems in Medical Imaging with Score-Based Generative Models” by Y Song et al. Reconstructing medical images from partial measurements is …
In this talk, we discuss the paper : “Diffusion Posterior Sampling for Linear Inverse Problem Solving- A Filtering Perspective” by Z. Dou& Y. Song Diffusion models have achieved tremendous success …
Abstract: In this talk, we propose novel noise-free Bayesian optimization strategies that rely on a random exploration step to enhance the accuracy of Gaussian process surrogate models. The new algorithms …
