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Dynamical and topological hallmarks of regulatory networks driving phenotypic plasticity and heterogeneity in cancers
Dynamical and topological hallmarks of regulatory networks driving phenotypic plasticity and heterogeneity in cancers
This talk will be presented online. Zoom link: 997 8258 4700 (pw: 1234) Abstract: Metastasis and therapy resistance cause over 90% of cancer-related deaths. Despite extensive ongoing efforts, no unique genetic or mutational signature has emerged for metastasis. Instead, the ability of genetically identical cells to adapt reversibly by exhibiting multiple phenotypes (phenotypic/non-genetic heterogeneity) and …