기초과학연구원 의생명수학그룹
Abstract: 1. The "temporal information code" of insulin action: a bottom-up approach One of the essential elements of signaling networks is to encode information from a wide variety of inputs …
Abstract: Cooperation means that one individual pays a cost for another to receive a benefit. Cooperation can be at variance with natural selection. Why should you help competitors? Yet cooperation …
Abstract: Multi-omics technologies, and in particular those with single-cell and spatial resolution, provide unique opportunities to study the deregulation of intra- and inter-cellular signaling processes in disease. I will present …
Abstract: Many questions in everyday life as well as in research are causal in nature: How would the climate change if we lower train prices or will my headache go …
Abstract: We will present a new approach to develop a data-driven, learning-based framework for predicting outcomes of biophysical systems and for discovering hidden mechanisms and pathways from noisy data. We …
Abstract: The well-known two-process model of sleep regulation makes accurate predictions of sleep timing and duration, as well as neurobehavioral performance, for a variety of acute sleep deprivation and nap …
Abstract: TBD
Abstract: Stochasticity in gene expression is an important source of cell-to-cell variability (or noise) in clonal cell populations. So far, this phenomenon has been studied using the Gillespie Algorithm, or …
Abstract: Cell fate specification is a dynamic process during which gene regulatory networks (GRNs) transition between different states and define cell type-specific patterns of gene expression. Identifying such cell type-specific …
Abstract: Typically, the mathematical description of reaction networks involves a system of parameter-dependent ordinary differential equations. Generally, one is interested in the qualitative and quantitative behavior of solutions in various …
Abstract: Almost all biological systems possess the ability to gather environmental information and modulate their behaviors to adaptively respond to changing environments. While animals excel at sensing odors, even simple …
Abstract: The Hypothalamic-Pituitary-Adrenal (HPA) axis is the key regulatory pathway responsible for maintaining homeostasis under conditions of real or perceived stress. Endocrine responses to stressors are mediated by adrenocorticotrophic hormone …
