기초과학연구원 의생명수학그룹
Abstract: Typically, the mathematical description of reaction networks involves a system of parameter-dependent ordinary differential equations. Generally, one is interested in the qualitative and quantitative behavior of solutions in various …
We will discuss about “A data-driven approach for timescale decomposition of biochemical reaction networks”, Amir Akbari, Zachary B. Haiman, Bernhard O. Palsson, bioRxiv (2023) Abstract Understanding the dynamics of biological …
We will discuss about “Power spectral estimate for discrete data”, Nobert Marwan and Tobias Braun, Chaos (2023). Abstract The identification of cycles in periodic signals is a ubiquitous problem …
Abstract: Almost all biological systems possess the ability to gather environmental information and modulate their behaviors to adaptively respond to changing environments. While animals excel at sensing odors, even simple …
We will discuss about "AutoScore:A Machine Learning–Based Automatic Clinical Score Generator and Its Application to Mortality Prediction Using Electronic Health Records", Xie, Feng, et al., JMIR medical informatics 8.10 (2020): e21798. …
We will discuss about “Significance analysis for clustering with single-cell RNA-sequencing data”, Grabski, Isabella N., Kelly Street, and Rafael A. Irizarry., Nature Methods (2023): 1-7. Abstract Unsupervised clustering of single-cell …
Abstract: The Hypothalamic-Pituitary-Adrenal (HPA) axis is the key regulatory pathway responsible for maintaining homeostasis under conditions of real or perceived stress. Endocrine responses to stressors are mediated by adrenocorticotrophic hormone …
Abstract: Interpreting data using mechanistic mathematical models provides a foundation for discovery and decision-making in all areas of science and engineering. Key steps in using mechanistic mathematical models to interpret …
We will discuss about "Uncertainty quantified discovery of chemical reaction systems via Bayesian scientific machine learning." bioRxiv (2023): 2023-09. Abstract The recently proposed Chemical Reaction Neural Network (CRNN) discovers …
Abstract: Surface Plasmon Resonance (SPR) assays are a standard approach for quantifying kinetic parameters in antibody-antigen binding reactions. Classical SPR approaches ignore the bivalent structure of antibodies, and use simplified …
Abstract: I will report on some recent results on modelling the heart, the external circulation, and their application to problems of clinical relevance. I will show that a proper integration …
