기초과학연구원 의생명수학그룹
Abstract: Biological phenomena are notorious for crossing several temporal and spatial scales. While often it may be sufficient to focus on a single scale, it is not rare that we …
This presentation introduces an approach for estimating parameter distributions in dynamic systems modeled by differential equations. Traditional parameter estimation techniques often struggle with Repeated Cross-Sectional (RCS) data, characteristic of many …
Abstract: In typical single-cell RNA-seq (scRNA-seq) data analysis, a clustering algorithm is applied to find discrete cell clusters as putative cell types, and then a statistical test is employed to …
We will discuss about “Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming”, Cell (2019). Abstract Understanding the molecular programs that guide differentiation during development is a …
We will discuss about “PenDA, a rank-based method for personalized differential analysis: Application to lung cancer” Plos Computational Biology (2020). Abstract The hopes of precision medicine rely on our capacity …
Abstract: The Downing lab investigates the intricate biophysical interactions between cells and their environment, elucidating their role in modulating adult cell behavior and phenotypic transitions via epigenetic regulation of gene …
We will discuss about “Data driven governing equations approximation using deep neural networks” Journal of Computational Physics (2019). Abstract We present a numerical framework for approximating unknown governing equations using …
In this talk, we discuss the paper "Inferring Causal Gene Regulatory Networks from Coupled Single-Cell Expression Dynamics Using Scribe", by Xiaojie Qiu et.al., Cell Syst. 2020. Abstract Here, we present …
In this talk, we discuss the paper, "MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data" by Siyao Liu et.al. Genome Biology, 2024. Abstract Single-cell …
In this talk, we will discuss the paper, "A modified shuffled frog leaping algorithm with inertia weight", by Zhuanzhe Zhao et.al. , Scientific Reports, 2024. Abstract The shuffled frog leaping …
I present time delay estimation problems in astronomy as a part of time delay cosmography to infer the Hubble constant, the current expansion rate of the Universe. Time delay cosmography …
In this talk, we discuss the paper "Holimap: an accurate and efficient method for solving stochastic gene network dynamics" by Chen Jia and Ramon Grima, bioRxiv, 2024. Abstract Gene-gene interactions are crucial to …