기초과학연구원 의생명수학그룹
Abstract: Reconstruction of gene regulatory networks (GRNs) is a powerful approach to capture a prioritized gene set controlling cellular processes. In our previous study, we developed TENET a GRN reconstructor …
We will discuss about "The timing of cellular events: a stochastic vs deterministic perspective", bioRxiv (2023): 2023-07. Abstract Changes in cell state are driven by key molecular events whose timing …
We will discuss about "Linear mapping approximation of gene regulatory networks with stochastic dynamics", Nature communications 9.1 (2018): 3305. Abstract The presence of protein–DNA binding reactions often leads to analytically …
We will discuss about “A trade-off in controlling upstream and downstream noise in signaling networks”, bioRxiv (2023): 2023-08. Abstract Signal transduction, underpinning the function of a variety of biological systems, …
Abstract: Cell-to-cell variability in gene expression exists even in a homogeneous population of cells. Dissecting such cellular heterogeneity within a biological system is a prerequisite for understanding how a biological …
Program table: Topic Talk+Q&A Presenter Title Model reduction 9:00-9:10 Hyeong Jun Jang Accurate and precise estimation in enzyme inihibition 9:10-9:20 Seolah Shin Beyond Homogeneity: Assessing the Validity of the Michaelis–Menten …
Abstract: Through the past decades, electrophysiological experiments have revealed that extracellular electrical potential of brain show diverse rhythmic activity. Called ‘Local Field Potential(LFP)’, those rhythmic activities are thought to reflect …
We will discuss about “Anticipating the occurrence and type of critical transitions”, Science Advances 9.1 (2023): eabq4558. Abstract Critical transition can occur in many real-world systems. The ability to …
We will discuss about “A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples ”, Nature communications 14.1 (2023): 7286. Abstract Pseudotime analysis with single-cell RNA-sequencing (scRNA-seq) data …
Abstract: The regulation and maintenance of an organ’s shape and structure is a major outstanding question in developmental biology. The Drosophila wing imaginal disc serves as a powerful system for …
We will discuss about "Reduced model for female endocrine dynamics: Validation and functional variations." Mathematical Biosciences 358 (2023): 108979. Abstract A normally functioning menstrual cycle requires significant crosstalk between hormones originating in …
We will discuss about “Transcriptome-wide analysis of cell cycle-dependent bursty gene expression from single-cell RNA-seq data using mechanistic model-based inference”, bioRxiv (2024) Abstract Bursty gene expression is quantified by two …