기초과학연구원 의생명수학그룹
Abstract: Biological phenomena are notorious for crossing several temporal and spatial scales. While often it may be sufficient to focus on a single scale, it is not rare that we …
This presentation introduces an approach for estimating parameter distributions in dynamic systems modeled by differential equations. Traditional parameter estimation techniques often struggle with Repeated Cross-Sectional (RCS) data, characteristic of many …
Abstract: In typical single-cell RNA-seq (scRNA-seq) data analysis, a clustering algorithm is applied to find discrete cell clusters as putative cell types, and then a statistical test is employed to …
We will discuss about “Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming”, Cell (2019). Abstract Understanding the molecular programs that guide differentiation during development is a …
We will discuss about “PenDA, a rank-based method for personalized differential analysis: Application to lung cancer” Plos Computational Biology (2020). Abstract The hopes of precision medicine rely on our capacity …
Abstract: The Downing lab investigates the intricate biophysical interactions between cells and their environment, elucidating their role in modulating adult cell behavior and phenotypic transitions via epigenetic regulation of gene …
We will discuss about “IData driven governing equations approximation using deep neural networks” Journal of Computational Physics (2019). Abstract We present a numerical framework for approximating unknown governing equations using …
