Journal Club

We will discuss about “Integration of Neural Network-Based Symbolic Regression in Deep Learning for Scientific Discovery” IEEE Transactions on neural networks and learning systems 32.9 (2020): 4166-4177. Abstract Symbolic regression is a powerful technique to discover analytic equations that describe data, which can lead to explainable models and the ability to predict unseen data. In …

We will discuss about "AI Feynman: A physics-inspired method for symbolic regression",Science Advances 6.16 (2020): eaay2631. Abstract A core challenge for both physics and artificial intelligence (AI) is symbolic regression: finding a symbolic expression that matches data from an unknown function. Although this problem is likely to be NP-hard in principle, functions of practical interest …

We will discuss about "The timing of cellular events: a stochastic vs deterministic perspective", bioRxiv (2023): 2023-07.   Abstract Changes in cell state are driven by key molecular events whose timing can often be measured experimentally. Of particular interest is the time taken for the levels of RNA or protein molecules to reach a critical threshold …

We will discuss about "Linear mapping approximation of gene regulatory networks with stochastic dynamics", Nature communications 9.1 (2018): 3305.   Abstract The presence of protein–DNA binding reactions often leads to analytically intractable models of stochastic gene expression. Here we present the linear-mapping approximation that maps systems with protein–promoter interactions onto approximately equivalent systems with no binding …

We will discuss about “A trade-off in controlling upstream and downstream noise in signaling networks”, bioRxiv (2023): 2023-08.   Abstract Signal transduction, underpinning the function of a variety of biological systems, is inevitably affected by fluctuations. It remains intriguing how the timescale of a signaling network relates to its capability of noise control, specifically, whether long …