기초과학연구원 의생명수학그룹
Collective cell movement is critical to the emergent properties of many multicellular systems including microbial self-organization in biofilms, wound healing, and cancer metastasis. However, even the best-studied systems lack a …
We introduce a sufficient graphical model by applying the recently developed nonlinear sufficient dimension reduction techniques to the evaluation of conditional independence. The graphical model is nonparametric in nature, as …
Abstract: TBA
We propose a kernel-based estimator to predict the mean response trajectory for sparse and irregularly measured longitudinal data. The kernel estimator is constructed by imposing weights based on the subject-wise …
TBA
To understand nonparametric regression, we should know first what the parametric model is. Simply speaking, the parametric regression model consists of many assumptions and the nonparametric regression model eases the assumptions. …
Abstract Mathematical models of biological systems, including neurons, often feature components that evolve on very different timescales. Mathematical analysis of these multi-timescale systems can be greatly simplified by partitioning them …
Abstract: Physiological needs evoke motivational drives to produce natural behaviours for survival. However, the temporally intertwined dynamics of need and motivation have made it challenging to differentiate these two components …
Abstract: Reconstruction of gene regulatory networks (GRNs) is a powerful approach to capture a prioritized gene set controlling cellular processes. In our previous study, we developed TENET a GRN reconstructor …
Abstract: Cell-to-cell variability in gene expression exists even in a homogeneous population of cells. Dissecting such cellular heterogeneity within a biological system is a prerequisite for understanding how a biological …