Jong Kyoung Kim, Dissecting cellular heterogeneity and plasticity in adipose tissue
Jong Kyoung Kim, Dissecting cellular heterogeneity and plasticity in adipose tissue
Abstract: Cell-to-cell variability in gene expression exists even in a homogeneous population of cells. Dissecting such cellular heterogeneity within a biological system is a prerequisite for understanding how a biological system is developed, homeostatically regulated, and responds to external perturbations. Single-cell RNA sequencing (scRNA-seq) allows the quantitative and unbiased characterization of cellular heterogeneity by providing …