Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation
Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation
We will discuss about “Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation”, Li et. al., Cell Systems, 2018 Abstract Gene regulation is a complex non-equilibrium process. Here, we show that quantitating the temporal regulation of key gene states (transcriptionally inactive, active, and refractory) provides a parsimonious framework for analyzing gene regulation. Our …