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Stem cell dynamics in the intestine and stomach

January 4 @ 11:10 am - 12:00 pm KST

B378 Seminar room, IBS, 55 Expo-ro Yuseong-gu
Daejeon, 34126 Korea, Republic of
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Bon-Kyoung Koo
Institute of Molecular Biotechnology of the Austrian Academy of Sciences

In adult tissues, stem cells undergo clonal competition because they proliferate while the stem cell niche provides limited space. This clonal competition allows the selection of healthy stem cells over time as unfit stem cells tend to lose from the competition. It could also be a mechanism to select a supercompetitor with tumorigenic mutations, which may lead to tumorigenesis. I am going to explain general concepts of clonal competition and how a simple model can explain the behaviour of adult stem cells. I will also show how geometric constraints affect the overall dynamics of stem cell competition.


January 4
11:10 am - 12:00 pm KST
Event Category:


Jae Kyoung Kim


B378 Seminar room, IBS
55 Expo-ro Yuseong-gu
Daejeon, 34126 Korea, Republic of
+ Google Map
IBS 의생명수학그룹 Biomedical Mathematics Group
기초과학연구원 수리및계산과학연구단 의생명수학그룹
대전 유성구 엑스포로 55 (우) 34126
IBS Biomedical Mathematics Group (BIMAG)
Institute for Basic Science (IBS)
55 Expo-ro Yuseong-gu Daejeon 34126 South Korea
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