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Highly accurate fluorogenic DNA sequencing with information theory–based error correction
Highly accurate fluorogenic DNA sequencing with information theory–based error correction
We will discuss about "Highly accurate fluorogenic DNA sequencing with information theory–based error correction", Chen et al., Nature Biotechnology (2017) Eliminating errors in next-generation DNA sequencing has proved challenging. Here we present error-correction code (ECC) sequencing, a method to greatly improve sequencing accuracy by combining fluorogenic sequencing-by-synthesis (SBS) with an information theory–based error-correction algorithm. ECC …