Cell signalling

We will discuss about "Ligand-receptor promiscuity enables cellular addressing", Su et al., bioRxiv (2021) In multicellular organisms, secreted ligands selectively activate, or “address,” specific target cell populations to control cell fate decision-making and other processes. Key cell-cell communication pathways use multiple promiscuously interacting ligands and receptors, provoking the question of how addressing specificity can emerge …