Abstract: In this talk, we propose novel noise-free Bayesian optimization strategies that rely on a random exploration step to enhance the accuracy of Gaussian process surrogate models. The new algorithms retain the ease of implementation of the classical GP-UCB algorithm, but the additional random exploration step accelerates their convergence, nearly achieving the optimal convergence rate. …
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Enhanced Gaussian Process Surrogates for Optimization and Sampling by Pure Exploration – Hwanwoo Kim
Enhanced Gaussian Process Surrogates for Optimization and Sampling by Pure Exploration – Hwanwoo Kim
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In this talk, we discuss the paper "Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model" by F. W. Townes et.al., Genome Biology, 2019. Abstract Single-cell RNA-Seq (scRNA-Seq) profiles gene expression of individual cells. Recent scRNA-Seq datasets have incorporated unique molecular identifiers (UMIs). Using negative controls, we show UMI counts follow … |
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In this talk, we discuss the paper "CARE as a wearable derived feature linking circadian amplitude to human cognitive functions" by Shuya Cui et.al., npj Digital Medicine, 2023. Abstract Circadian rhythms are crucial for regulating physiological and behavioral processes. Pineal hormone melatonin is often used to measure circadian amplitude but its collection is costly and … |
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Over the past decade, the phase behavior of biomolecules has garnered significant attention, particularly due to its biological implications, such as the reversible formation and dissociation of biomolecular condensates. These condensates perform diverse and essential functions within cells, including the acceleration of chemical reactions. Recent advances aim to uncover the fundamental principles of these systems … |
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The field of sleep science is rapidly advancing, with increasing attention focused on unraveling the mystery of sleep across various scientific domains. Sleep medicine, which emerged from scientific research on sleep, is a highly important field that can enhance the quality of life and health. Since sleep medicine requires the integration of various specialized knowledge, … |
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In this talk, we discuss the paper "Plausible, robust biological oscillations through allelic buffering" by F-S. Hsieh et.al, Cell Systems, 2024. at the Journal Club. Abstract Biological oscillators can specify time- and dose-dependent functions via dedicated control of their oscillatory dynamics. However, how biological oscillators, which recurrently activate noisy biochemical processes, achieve robust oscillations remains … |
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In this talk, we discuss the paper "Self-supervised learning of accelerometer data provides new insights for sleep and its association with mortality" by H. Yuan et.al, npj digital medicine, 2024, at the Journal Club. Abstract Sleep is essential to life. Accurate measurement and classification of sleep/wake and sleep stages is important in clinical studies for … |
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