기초과학연구원 의생명수학그룹
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Abstract: The realization that microbiomes, associated with virtually all multicellular organisms, have tremendous impact on their host health is considered as one of the most important scientific discoveries in the last decade. The host associated microbiomes, composed of tens to hundreds of co-existing microbial species, are highly heterogenous at multiple scales (e.g. between different hosts … |
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The talk will be hybrid, participants may join via Zoom with the following link: https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09 |
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In this talk, we discuss the paper, "Predicting multiple observations in complex systems through low-dimensional embeddings", by Tao Wu et. al., Nature Communications, 2024. Zoom : https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09 Abstract Forecasting all components in complex systems is an open and challenging task, possibly due to high dimensionality and undesirable predictors. We bridge this gap by proposing a data-driven … |
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In this talk, we discuss the paper "Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage" by Zhiwei Huang, et. al., bioRxiv, 2024. Zoom : https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09 Abstract Cells must adopt flexible regulatory strategies to make decisions regarding their fate, including differentiation, apoptosis, or survival in the face of … |
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In this talk, we discuss the paper "Achieving Occam’s razor: Deep learning for optimal model reduction" by Botond B. Antal et.al., PLOS Computational Biology, 2024. Abstract All fields of science depend on mathematical models. Occam’s razor refers to the principle that good models should exclude parameters beyond those minimally required to describe the systems they represent. This … |
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Abstract: The study of sleep and circadian rhythms at scale requires novel technologies and approaches that are valid, cost effective and do not pose much of a burden to the participant. Here we will present our recent studies in which we have evaluated several classes of technologies and approaches including wearables, nearables, blood based biomarkers … |
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In this talk we discuss the paper "Mathematical model for the distribution of DNA replication origins" by Alessandro de Moura and Jens Karschau, Physical Review E, 2024. Abstract DNAreplication in yeast and in many other organisms starts from well-defined locations on the DNA known as replication origins. The spatial distribution of these origins in the genome is particularly … |
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