Abstract Background : Excess mortality captures both the direct and indirect impacts of the pandemic. We examine (1) within-country heterogeneity by healthcare access over distinct viral waves in Korea, and (2) cross-country associations between excess mortality and preparedness (Global Health Security, GHS), stratified by IMF development stage. Methods : Study 1 assembled a region-level panel …
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![]() Abstract Many processes in the life sciences are inherently multi-scale and dynamic. Spatial structures and patterns vary across levels of organisation, from molecular to multi-cellular to multi-organism. With more sophisticated mechanistic models and data available, quantitative tools are needed to study their evolution in space and time. Topological data analysis (TDA) provides a multi-scale summary … |
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![]() Abstract Smartphones and wearable devices provide a major opportunity to transform our understanding of the mechanisms, determinants, and consequences of diseases. For example, around 9 in 10 people own a smartphone in the United Kingdom, while one-fifth of US adults own wearable technologies. This high level of device ownership means that many people could contribute … |
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In this talk, we discuss the paper "Simulating the Spread of Infection in Networks with Quantum Computers" by Xiaoyang Wang, Yinchenguang Lyu, Changyu Yao and Xiao Yuan, Physical Review Applied, vol.19, 064035 (2023). Abstract We propose to use quantum computers to simulate infection spreading in networks. We first show the analogy between the infection distribution … |
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In this talk, we discuss the paper "Coarse-graining network flow through statistical physics and machine learning" by Z. Zhang, et al., Nat. Comm., 2025. Abstract Information dynamics plays a crucial role in complex systems, from cells to societies. Recent advances in statistical physics have made it possible to capture key network properties, such as flow … |
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![]() Abstract I will present a talk on "Dynamical data science and AI" for quantifying dynamical biological processes, disease progressions and various phenotypes, including dynamic network biomarkers (DNB) for early-warning signals of critical transitions, spatial-temporal information (STI) transformation for short-term time-series prediction, knockoff conditional mutual information (KOCMI) for quantifying interventional causality, partial cross-mapping (PCM) for causal … |
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In this talk, we discuss the paper "Dosing Time of Day Impacts the Safety of Antiarrhythmic Drugs in a Computational Model of Cardiac Electrophysiology" by Ning Wei and Casey O Diekman, J. Biol. Rhythms, 2025. Abstract Circadian clocks regulate many aspects of human physiology, including cardiovascular function and drug metabolism. Administering drugs at optimal times of … |
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