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A lognormal Poisson model for single cell transcriptomic normalization – Fred Wright
A lognormal Poisson model for single cell transcriptomic normalization – Fred Wright
Abstract The advent of single-cell transcriptomics has brought a greatly improved understanding of the heterogeneity of gene expression across cell types, with important applications in developmental biology and cancer research. Single-cell RNA sequencing datasets, which are based on tags called universal molecular identifiers, typically include a large number of zeroes. For such datasets, genes with …
