In this talk, we discuss the paper "Dosing Time of Day Impacts the Safety of Antiarrhythmic Drugs in a Computational Model of Cardiac Electrophysiology" by Ning Wei and Casey O Diekman, J. Biol. Rhythms, 2025. Abstract Circadian clocks regulate many aspects of human physiology, including cardiovascular function and drug metabolism. Administering drugs at optimal times of …
Journal Club
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In this talk, we discuss the paper "Principled PCA separates signal from noise in omics count data" by Jay S. Stanley III et al., bioarxiv, 2025. Abstract Principal component analysis (PCA) is indispensable for processing high-throughput omics datasets, as it can extract meaningful biological variability while minimizing the influence of noise. However, the suitability of PCA … |
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In this talk, we discuss the paper "Modeling personalized heart rate response to exercise and environmental factors with wearables data" by Nazaret et al., npj digital medicine, 2023. Abstract Heart rate (HR) response to workout intensity re ects tness and cardiorespiratory health. Physiological models have been developed to describe such heart rate dynamics and characterize … |
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