Journal Club

We will discuss about “scPrisma infers, filters and enhances topological signals in single-cell data using spectral template matching”, Karin, Jonathan, Yonathan Bornfeld, and Mor Nitzan., Nature Biotechnology (2023): 1-10. Abstract Single-cell RNA sequencing has been instrumental in uncovering cellular spatiotemporal context. This task is challenging as cells simultaneously encode multiple, potentially cross-interfering, biological signals. Here we …

We will discuss about “The singularity response reveals entrainment properties of the plant circadian clock”, Masuda, Kosaku, et al., Nature Communications 12.1 (2021): 864. Abstract Circadian clocks allow organisms to synchronize their physiological processes to diurnal variations. A phase response curve allows researchers to understand clock entrainment by revealing how signals adjust clock genes differently …

We will discuss about “ The Internal Model Principle for Biomolecular Control Theory ”, Gupta, Ankit, and Mustafa Khammash., IEEE Open Journal of Control Systems 2 (2023): 63-69.   Abstract The well-known Internal Model Principle (IMP) is a cornerstone of modern control theory. It stipulates the necessary conditions for asymptotic robustness of disturbance-prone dynamical systems …