We will discuss about "Absolute concentration robustness in networks with low-dimensional stoichiometric subspace", Meshkat, Nicolette, Anne Shiu, and Angelica Torres., Vietnam Journal of Mathematics 50.3 (2022): 623-651. Abstract: A reaction system exhibits “absolute concentration robustness” (ACR) in some species if the positive steady-state value of that species does not depend on initial conditions. Mathematically, this …
Journal Club
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We will discuss about "Rhythmicity is linked to expression cost at the protein level but to expression precision at the mRNA level", David Laloum, and Marc Robinson-Rechavi, PLoS computational biology 18.9 (2022): e1010399. Abstract: Many genes have nycthemeral rhythms of expression, i.e. a 24-hours periodic variation, at either mRNA or protein level or both, and … |
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We will discuss about "Inferring microenvironmental regulation of gene expression from single-cell RNA sequencing data using scMLnet with an application to COVID-19", Cheng, Jinyu, et al., Briefings in bioinformatics 22.2 (2021): 988-1005. Abstract: Inferring how gene expression in a cell is influenced by cellular microenvironment is of great importance yet challenging. In this study, we … |
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We will discuss about "Model Reduction for the Chemical Master Equation: an Information-Theoretic Approach", Öcal, Kaan, Guido Sanguinetti, and Ramon Grima., arXiv preprint arXiv:2210.05329 (2022). Abstract: The complexity of mathematical models in biology has rendered model reduction an essential tool in the quantitative biologist's toolkit. For stochastic reaction networks described using the Chemical Master Equation, commonly … |
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