Journal Club

We will discuss about “Detecting and quantifying causal associations in large nonlinear time series datasets”, Runge et al., Science Advances, 2019 Identifying causal relationships and quantifying their strength from observational time series data are key problems in disciplines dealing with complex dynamical systems such as the Earth system or the human body. Data-driven causal inference …

We will discuss about “Solving Singular Control Problems in Mathematical Biology, Using PASA”, Atkins et al., arXiv, 2020 In this paper, we will demonstrate how to use a nonlinear polyhedral constrained optimization solver called the Polyhedral Active Set Algorithm (PASA) for solving a general singular control problem. We present methods of discretizing a general optimal …

We will discuss about “A Random Matrix Theory Approach to Denoise Single-Cell Data”, Aparicio et al., Patterns, 2020 Single-cell technologies provide the opportunity to identify new cellular states. However, a major obstacle to the identification of biological signals is noise in single-cell data. In addition, single-cell data are very sparse. We propose a new method …