We will discuss about "Neural network aided approximation and parameter inference of stochastic models of gene expression", Jian et al., bioRxiv (2020). Non-Markov models of stochastic biochemical kinetics often incorporate explicit time delays to effectively model large numbers of intermediate biochemical processes. Analysis and simulation of these models, as well as the inference of their …
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We will discuss about "Ligand-receptor promiscuity enables cellular addressing", Su et al., bioRxiv (2021) In multicellular organisms, secreted ligands selectively activate, or “address,” specific target cell populations to control cell fate decision-making and other processes. Key cell-cell communication pathways use multiple promiscuously interacting ligands and receptors, provoking the question of how addressing specificity can emerge … |
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