Rationalizing Therapeutics: Mathematical Insights into Drug and Cell Therapy Development – Seokjoo Chae

Mathematical modeling provides essential quantitative insights that accelerate drug and cell therapy development. In this presentation, we utilize kinetic frameworks to optimize the design of molecular glues by elucidating their biophysical determinants and identify a key target for NK cell-mediated immunotherapy through systematic data analysis. Collectively, we demonstrate how mathematical strategies can effectively guide and advance the development of next-generation therapeutics.