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Correction of a Faulty Gene in Human Embryos

Correction of a Faulty Gene in Human Embryos Published in Nature, CRISPR-Cas9 genetic scissors open up new pathways to treat and prevent genetic diseasesThe scientists used the groundbreaking gene-editing tool CRISPR-Cas9 to repair the DNA piece that causes a common genetic heart disease known as hypertrophic cardiomyopathy. This technique would prevent the disease from being inherited by succeeding generations.DETAIL VIEW

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New MRI Contrast Agent Tested on Big Animals

New MRI Contrast Agent Tested on Big AnimalsExperiments in dogs, rabbits and monkeys show the efficacy and biocompatibility of a new MRI/MRA contrast agent in detecting stroke. This T1 MRI contrast agent based on ultrasmall iron oxide nanoparticles could become a possible alternative to clinically used gadolinium-based agents.
The top causes of death worldwide, ischemic heart diseases and stroke, together with another major source of illness, that is cancer, require proper imaging of blood vessels.
date2017-08-01

Competition for Survival Signals Maintains Immune Balance

Competition for Survival Signals Maintains Immune BalanceAlthough scarce, the recently discovered innate lymphoid cells vie with T cells for a shared source of interleukin-7, which helps them to survive. These findings could deepen our understanding of immune memory in vaccine and aging.
According to a new study published in the journal Immunity, two types of immune cells compete for a shared source of proteins that allow them to survive.
date2017-07-27

Atlantic/Pacific Ocean Temperature Difference Fuels US Wildfires

Atlantic/Pacific Ocean Temperature Difference Fuels US WildfiresNew study shows that difference in water temperature between the Pacific and the Atlantic oceans together with global warming impact the risk of drought and wildfire in southwestern North America.
An international team of climate researchers from the US, South Korea and the UK has developed a new wildfire and drought prediction model for southwestern North America. Extending far beyond the current seasonal forecast, this study published in the journal Scientific Reports could benefit the economies with a variety of applications in agriculture, water management and forestry.
date2017-07-26

New Harmless Radiopaque Glue to Seal Bleeding and Guide Surgery

New Harmless Radiopaque Glue to Seal Bleeding and Guide SurgeryFirst nanoparticle-based adhesive with imaging contrast effect in CT and ultrasound was successfully tested in animals and showed less toxicity than the FDA-approved glue CA-Lp.
As open surgery has gradually been replaced by minimally-invasive and image-guided procedures, tissue adhesives are taking the place of sutures and surgical staples. With countless applications, including: bleeding embolization, angioplasty, stent insertion, and biopsy, among others, new surgical glues are highly desired in medical clinics.
date2017-07-19

Multi-Antioxidant Nanoparticles to Treat Sepsis

Multi-Antioxidant Nanoparticles to Treat SepsisFrom the energy sector to biology, ceria-zirconia nanoparticles remove free radicals and improve survival in animal models.
With an incidence of 31.5 million worldwide and a mortality of around 17%, sepsis remains the most common cause of death in hospitalized patients, even in industrialized countries where antibiotics and critical care facilities are readily available. While this disease begins as a serious infection, sepsis' life-threatening organ failure is due to an excessive inflammatory response. By overproducing oxygen free radicals, the immunity of the host itself paradoxically leads to an increase in morbidity and mortality.
date2017-07-13

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