Quinolinone derivative compound selectively binding to cysteine, peptide conjugate thereof, and antibody-drug conjugate comprising same

[특허 요약] The present disclosure relates to a quinolinone derivative compound selectively binding to cysteine, an amino acid- or peptide-conjugate thereof, and an antibody-drug conjugate comprising same. Since a conjugate with high chemoselectivity and high yield is formed through a radical pathway induced by visible light, the present disclosure can be applied in various ways to bioconjugation.

특허 등록번호

20230322821A

특허 출원번호

202118023920

출원일

2021.08.25

등록일

2023.10.12

국가

미국

출원인

기초과학연구원, 한국과학기술원

발명자

Sungwoo HONG, Jaebong JANG, Hangyeol CHOI, Myojeong KIM

중요 키워드

alkyl, alkoxy, aryl, independently, hydrogen