보유 특허 상세 정보를 불러오는 중입니다...
| 특허 상태 | 공개 |
| 출원인 | 기초과학연구원, 한국과학기술원 |
| 발명자 | Gou Young Koh, Jeomil BAE, Mi Jeong Kim, Jin-Sung Park, Su Jin Seo, Jaeryung KIM, Jang Ryul Park, Pilhan KIM, Wangyuhl OH |
| 출원번호 | 19757411 |
| 출원일 | 2019.02.19 |
| 등록번호 | 3755714A |
| 등록일 | 2022.02.16 |
| 중요 키워드 | angiopoietinantibodies |
The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention provides an angiogenesis inhibitor and a composition for prevention and treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
연관 기술이전 로딩 중...
연관 연구자 로딩 중...
ANTI-ANGIOPOIETIN-2 ANTIBODIES AND THEIR USES
[특허 요약] The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention provides an angiogenesis inhibitor and a composition for prevention and treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.
| 출원번호 | 출원일 |
| 2023175308 | 2023.10.10 |
| 종류코드 | |
| A | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 202218045964 | 2022.10.12 |
| 종류코드 | |
| B2 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 202016995707 | 2020.08.17 |
| 종류코드 | |
| B2 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 2019224694 | 2019.02.19 |
| 종류코드 | |
| B2 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 3091613 | 2019.02.19 |
| 종류코드 | |
| A1 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 201980014282 | 2019.02.19 |
| 종류코드 | |
| B | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 2020566520 | 2019.02.19 |
| 종류코드 | |
| B2 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 2020008663 | 2019.02.19 |
| 종류코드 | |
| A | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 1020190018769 | 2019.02.18 |
| 종류코드 | |
| A | |
| 외부 링크 | |