Partial skull replacements capable of monitoring in real time and delivering substances into brain tissue, and uses thereof

[특허 요약] The present invention relates to a partial skull replacement consisting of polydimethylsiloxane (PDMS) and a method of monitoring biological tissues within a skull using the partial skull replacement. The method of monitoring using the partial skull replacement of the present invention has a minimal influence on intracranial pressure and cerebrospinal fluid flow as compared to a conventional cranial window technique using glass, and, by way of visualizing biological tissues within a skull with enhanced clarity, is expected to be usefully employed as a method of monitoring biological tissues within the skull.

특허 등록번호

10639397B

특허 출원번호

201615068051

출원일

2016.03.11

등록일

2020.05.05

국가

미국

출원인

성균관대학교산학협력단, 기초과학연구원

발명자

Seong-Gi KIM, Minah SUH, Chaejeong HEO, Hyoung Won Baac

중요 키워드

skull, replacement, partial, pdms, monitoring