보유 특허 상세 정보를 불러오는 중입니다...
| 특허 상태 | 공개 |
| 출원인 | 기초과학연구원 |
| 발명자 | Sung Ik Cho, Jin-Soo Kim, Jaesuk Lee, Kayeong LIM |
| 출원번호 | 2023344227 |
| 출원일 | 2023.07.04 |
| 등록번호 | 2023344227A |
| 등록일 | 2025.05.08 |
| 중요 키워드 | dnafusion proteintarget |
The present invention relates a novel adenine deaminase variant, a fusion protein comprising the adenine deaminase variant, a base editing composition for A-to-G base editing in DNA comprising the fusion protein, and a method for A-to-G base editing in DNA comprising delivering the base editing composition to a cell containing a target DNA. The novel adenine deaminase variant can result in remarkably reduced off-target effects involving an unintended base alteration in DNA and/or RNA, and induce base editing only at a single nucleotide residue without any unintended off-target editing in the target DNA.
연관 기술이전 로딩 중...
연관 연구자 로딩 중...
Novel adenine deaminase variants and a method for base editing using the same
[특허 요약] The present invention relates a novel adenine deaminase variant, a fusion protein comprising the adenine deaminase variant, a base editing composition for A-to-G base editing in DNA comprising the fusion protein, and a method for A-to-G base editing in DNA comprising delivering the base editing composition to a cell containing a target DNA. The novel adenine deaminase variant can result in remarkably reduced off-target effects involving an unintended base alteration in DNA and/or RNA, and induce base editing only at a single nucleotide residue without any unintended off-target editing in the target DNA.
| 출원번호 | 출원일 |
| 1020257013429 | 2023.07.04 |
| 종류코드 | |
| A | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 202380067900 | 2023.07.04 |
| 종류코드 | |
| A | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 23868333 | 2023.07.04 |
| 종류코드 | |
| A1 | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 2025517270 | 2023.07.04 |
| 종류코드 | |
| A | |
| 외부 링크 | |
| 출원번호 | 출원일 |
| 2023009361 | 2023.07.04 |
| 종류코드 | |
| A1 | |
| 외부 링크 | |