{"id":5585,"date":"2022-04-07T02:00:00","date_gmt":"2022-01-06T17:00:00","guid":{"rendered":"https:\/\/www.ibs.re.kr\/bimag\/?post_type=tribe_events&p=5585"},"modified":"2022-02-24T09:23:21","modified_gmt":"2022-02-24T00:23:21","slug":"2022-04-07","status":"publish","type":"tribe_events","link":"https:\/\/www.ibs.re.kr\/bimag\/event\/2022-04-07\/","title":{"rendered":"Universal biology in adaptation and evolution: dimensional reduction, and fluctuation-response relationship"},"content":{"rendered":"

This talk will be presented online. Zoom link: 997 8258 4700<\/a> (pw: 1234)<\/p>\n

Abstract: A macroscopic theory for cellular states with steady-growth is presented, based on consistency between cellular growth and molecular replication, together with robustness of phenotypes against perturbations. Adaptive changes in high-dimensional phenotypes are shown to be restricted within a low-dimensional slow manifold, from which a macroscopic law for cellular states is derived, as is confirmed by adaptation experiments of bacteria under stress. The theory is extended to phenotypic evolution, leading to proportionality between phenotypic responses against genetic evolution and by environmental adaptation, which explains the evolutionary fluctuation-response relationship previously uncovered.\u00a0\u00a0<\/span><\/p>\n

References<\/b><\/p>\n

    \n
  1. Kaneko K., Life: An Introduction to Complex Systems Biology, Springer (2006)<\/span><\/li>\n
  2. K. Kaneko, C.Furusawa, T. Yomo, “Macroscopic phenomenology for cells in steady-growth state”, Phys.Rev.X(2015) 011014<\/span><\/li>\n
  3. C. Furusawa, K. Kaneko “Global Relationships in Fluctuation and Response in Adaptive Evolution”, J of Royal Society Interface <\/span>12<\/span><\/i>(2015), 20150482.<\/span><\/li>\n
  4. C. Furusawa, K. Kaneko ” Formation of Dominant Mode by Evolution in Biological Systems\u201d Phys. Rev. E 97(2018)042410<\/span><\/li>\n
  5. K. Kaneko, C. Furusawa \u201cMacroscopic Theory for Evolving Biological Systems Akin to Thermodynamics\u201d, Annual Rev. Biophys. (2018) 47, 273-290<\/span><\/li>\n
  6. A. Sakata and K. Kaneko, \u201c<\/span>Dimensional Reduction in Evolving Spin-Glass Model: Correlation of Phenotypic Responses to Environmental and Mutational Changes\u201d, Phys. Rev. Lett. (2020) 124, 218101<\/span><\/li>\n
  7. Q-Y. Tang and K. Kaneko, \u201c Dynamics-evolution correspondence in protein structures\u201d,\u00a0 Phys. Rev. Lett. (2021) 127, 098103<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    This talk will be presented online. Zoom link: 997 8258 4700 (pw: 1234) Abstract: A macroscopic theory for cellular states with steady-growth is presented, based on consistency between cellular growth … <\/p>\n

    Continue reading “Universal biology in adaptation and evolution: dimensional reduction, and fluctuation-response relationship”<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":5571,"template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","_uag_custom_page_level_css":"","_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[],"tribe_events_cat":[221],"class_list":["post-5585","tribe_events","type-tribe_events","status-publish","has-post-thumbnail","hentry","tribe_events_cat-biomedical-mathematics-colloquium","cat_biomedical-mathematics-colloquium","tribe-ext-events-control-list-event--live"],"yoast_head":"\nUniversal biology in adaptation and evolution: dimensional reduction, and fluctuation-response relationship - Biomedical Mathematics Group<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ibs.re.kr\/bimag\/event\/2022-04-07\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Universal biology in adaptation and evolution: dimensional reduction, and fluctuation-response relationship - Biomedical Mathematics Group\" \/>\n<meta property=\"og:description\" content=\"This talk will be presented online. 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