In this talk, we discuss the paper “A biological model of nonlinear dimensionality reduction” by K. Yoshida and T. Toyoizumi, Science Advances, 2025, at the Journal Club.<\/p>\n
Abstract<\/strong><\/p>\n Obtaining appropriate low-dimensional representations from high-dimensional sensory inputs in an unsupervised manner is essential for straightforward downstream processing. Although nonlinear dimensionality reduction methods such as\u00a0t<\/i>-distributed stochastic neighbor embedding (t<\/i>-SNE) have been developed, their implementation in simple biological circuits remains unclear. Here, we develop a biologically plausible dimensionality reduction algorithm compatible with\u00a0t<\/i>-SNE, which uses a simple three-layer feedforward network mimicking the\u00a0Drosophila<\/i>\u00a0olfactory circuit. The proposed learning rule, described as three-factor Hebbian plasticity, is effective for datasets such as entangled rings and MNIST, comparable to\u00a0t<\/i>-SNE. We further show that the algorithm could be working in olfactory circuits in Drosophila by analyzing the multiple experimental data in previous studies. We lastly suggest that the algorithm is also beneficial for association learning between inputs and rewards, allowing the generalization of these associations to other inputs not yet associated with rewards.<\/p>","excerpt":"","slug":"a-biological-model-of-nonlinear-dimensionality-reduction-shingo-gibo","image":false,"all_day":false,"start_date":"2025-03-14 14:00:00","start_date_details":{"year":"2025","month":"03","day":"14","hour":"14","minutes":"00","seconds":"00"},"end_date":"2025-03-14 16:00:00","end_date_details":{"year":"2025","month":"03","day":"14","hour":"16","minutes":"00","seconds":"00"},"utc_start_date":"2025-03-14 05:00:00","utc_start_date_details":{"year":"2025","month":"03","day":"14","hour":"05","minutes":"00","seconds":"00"},"utc_end_date":"2025-03-14 07:00:00","utc_end_date_details":{"year":"2025","month":"03","day":"14","hour":"07","minutes":"00","seconds":"00"},"timezone":"Asia\/Seoul","timezone_abbr":"KST","cost":"","cost_details":{"currency_symbol":"$","currency_code":"USD","currency_position":"prefix","values":[]},"website":"","show_map":false,"show_map_link":false,"hide_from_listings":false,"sticky":false,"featured":false,"categories":[{"name":"Journal Club","slug":"journal-club","term_group":0,"term_taxonomy_id":219,"taxonomy":"tribe_events_cat","description":"","parent":231,"count":207,"filter":"raw","id":219,"urls":{"self":"https:\/\/www.ibs.re.kr\/bimag\/wp-json\/tribe\/events\/v1\/categories\/219","collection":"https:\/\/www.ibs.re.kr\/bimag\/wp-json\/tribe\/events\/v1\/categories","up":"https:\/\/www.ibs.re.kr\/bimag\/wp-json\/tribe\/events\/v1\/categories\/231"}}],"tags":[],"venue":[],"organizer":[{"id":3971,"author":"3","status":"publish","date":"2021-02-23 18:10:12","date_utc":"2021-02-23 09:10:12","modified":"2021-02-23 18:10:12","modified_utc":"2021-02-23 09:10:12","url":"https:\/\/www.ibs.re.kr\/bimag\/organizer\/jae-kyoung-kim\/","organizer":"Jae Kyoung Kim","slug":"jae-kyoung-kim","email":"jaekkim@kaist.ac.kr","json_ld":{"@type":"Person","name":"Jae Kyoung Kim","description":"","url":"","telephone":"","email":"jaekkim@kaist.ac.kr","sameAs":""},"global_id":"www.ibs.re.kr\/bimag?id=3971","global_id_lineage":["www.ibs.re.kr\/bimag?id=3971"]}],"custom_fields":[],"json_ld":{"@context":"http:\/\/schema.org","@type":"Event","name":"A biological model of nonlinear dimensionality reduction – Shingo Gibo","description":"<p>In this talk, we discuss the paper "A biological model of nonlinear dimensionality reduction" by K. Yoshida and T. Toyoizumi, Science Advances, 2025, at the Journal Club. Abstract Obtaining appropriate … <\/p>\\n<p class="link-more"><a href="https:\/\/www.ibs.re.kr\/bimag\/event\/a-biological-model-of-nonlinear-dimensionality-reduction-shingo-gibo\/" class="more-link">Continue reading<span class="screen-reader-text"> "A biological model of nonlinear dimensionality reduction – Shingo Gibo"<\/span><\/a><\/p>\\n","url":"https:\/\/www.ibs.re.kr\/bimag\/event\/a-biological-model-of-nonlinear-dimensionality-reduction-shingo-gibo\/","eventAttendanceMode":"https:\/\/schema.org\/OfflineEventAttendanceMode","eventStatus":"https:\/\/schema.org\/EventScheduled","startDate":"2025-03-14T14:00:00+09:00","endDate":"2025-03-14T16:00:00+09:00","organizer":{"@type":"Person","name":"Jae Kyoung Kim","description":"","url":"","telephone":"","email":"jaekkim@kaist.ac.kr","sameAs":""},"performer":"Organization"}}