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X-WR-CALNAME:Biomedical Mathematics Group
X-ORIGINAL-URL:https://www.ibs.re.kr/bimag
X-WR-CALDESC:Events for Biomedical Mathematics Group
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TZID:Asia/Seoul
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TZOFFSETFROM:+0900
TZOFFSETTO:+0900
TZNAME:KST
DTSTART:20250101T000000
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BEGIN:VEVENT
DTSTART;TZID=Asia/Seoul:20260605T100000
DTEND;TZID=Asia/Seoul:20260605T120000
DTSTAMP:20260527T114806
CREATED:20260429T070216Z
LAST-MODIFIED:20260527T003414Z
UID:12396-1780653600-1780660800@www.ibs.re.kr
SUMMARY:Chaos Meets Attention: Transformers for Large-Scale Dynamical Prediction- Gyuyoung Hwang
DESCRIPTION:In this talk\, we discuss the paper “Chaos Meets Attention: Transformers for Large-Scale Dynamical Prediction” by Yi He et al.\, ICML Poster\, 2025. \nAbstract: \nGenerating long-term trajectories of dissipative chaotic systems autoregressively is a highly challenging task. The inherent positive Lyapunov exponents amplify prediction errors over time. Many chaotic systems possess a crucial property — ergodicity on their attractors\, which makes long-term prediction possible. State-of-the-art methods address ergodicity by preserving statistical properties using optimal transport techniques. However\, these methods face scalability challenges due to the curse of dimensionality when matching distributions. To overcome this bottleneck\, we propose a scalable transformer-based framework capable of stably generating long-term high-dimensional and high-resolution chaotic dynamics while preserving ergodicity. Our method is grounded in a physical perspective\, revisiting the Von Neumann mean ergodic theorem to ensure the preservation of long-term statistics in the L2 space. We introduce novel modifications to the attention mechanism\, making the transformer architecture well-suited for learning large-scale chaotic systems. Compared to operator-based and transformer-based methods\, our model achieves better performances across five metrics\, from short-term prediction accuracy to long-term statistics. In addition to our methodological contributions\, we introduce new chaotic system benchmarks: a machine learning dataset of 140 snapshots of turbulent channel flow and a processed high-dimensional Kolmogorov Flow dataset\, along with various evaluation metrics for both short- and long-term performances. Both are well-suited for machine learning research on chaotic systems.
URL:https://www.ibs.re.kr/bimag/event/bridging-known-and-unknown-dynamics-by-transformer-based-machine-learning-inference-from-sparse-observations-gyuyoung-hwang/
LOCATION:B232 Seminar Room\, IBS\, 55 Expo-ro Yuseong-gu\, Daejeon\, Daejeon\, 34126\, Korea\, Republic of
CATEGORIES:Journal Club
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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BEGIN:VEVENT
DTSTART;TZID=Asia/Seoul:20260612T100000
DTEND;TZID=Asia/Seoul:20260612T120000
DTSTAMP:20260527T114806
CREATED:20260520T075146Z
LAST-MODIFIED:20260520T075146Z
UID:12428-1781258400-1781265600@www.ibs.re.kr
SUMMARY:Insulin resistance prediction from wearables and routine blood biomarkers - Dongju Lim
DESCRIPTION:In this talk\, we discuss the paper “Insulin resistance prediction from wearables and routine blood biomarkers” by Ahmed A. Metwally et al.\, Nature\, 2026. \n  \nAbstract: \nInsulin resistance (IR)\, a primary precursor to type 2 diabetes\, is characterized by impaired insulin action in tissues1. However\, diagnostic methods remain expensive and inaccessible\, which hinders early intervention2\,3. Here we present the WEAR-ME study\, a large\, remotely conducted study of IR (n = 1\,165 participants; median body mass index (BMI) = 28 kg m−2\, median age = 45 years\, median haemoglobin A1c (HbA1c) = 5.4%) that uses time-series data from wearable devices and routine blood biomarkers to train deep neural networks against a ground-truth measure of IR (homeostatic model assessment of IR; HOMA-IR). Using a HOMA-IR cut-off of 2.9\, our multimodal model achieved robust performance (area under the receiver operating characteristic curve (AUROC) = 0.80\, sensitivity = 76%\, specificity = 84%) with data from wearable devices\, together with demographic and routine blood biomarker data. To enhance the use of time-series data from wearables\, we fine-tuned a wearable foundation model (WFM) pretrained on 40 million hours of sensor data. In an independent validation cohort (n = 72)\, a model integrating WFM-derived representations with demographic data surpassed a demographics-only baseline (AUROC = 0.75 versus 0.66). Moreover\, adding WFM-derived representations to a model with demographics\, fasting glucose and a lipid panel substantially improved performance\, compared with an identical model without data from wearables (AUROC = 0.88 versus 0.76). We integrate IR prediction into a large language model to contextualize the results and facilitate personalized recommendations. This work establishes a scalable\, accessible framework for the early detection of metabolic risk\, which could enable timely lifestyle interventions to prevent progression to type 2 diabetes.
URL:https://www.ibs.re.kr/bimag/event/insulin-resistance-prediction-from-wearables-and-routine-blood-biomarkers-dongju-lim/
LOCATION:B232 Seminar Room\, IBS\, 55 Expo-ro Yuseong-gu\, Daejeon\, Daejeon\, 34126\, Korea\, Republic of
CATEGORIES:Journal Club
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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