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X-WR-CALDESC:Events for Biomedical Mathematics Group
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TZOFFSETFROM:+0900
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DTSTART:20230101T000000
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BEGIN:VEVENT
DTSTART;TZID=Asia/Seoul:20241011T140000
DTEND;TZID=Asia/Seoul:20241011T160000
DTSTAMP:20260424T021510
CREATED:20240923T012824Z
LAST-MODIFIED:20240923T012824Z
UID:10095-1728655200-1728662400@www.ibs.re.kr
SUMMARY:Eui Min Jeong\, A frequency-amplitude coordinator and its optimal energy consumption for biological oscillators
DESCRIPTION:In this talk\, we discuss the paper\, “A frequency-amplitude coordinator and its optimal energy consumption for biological oscillators”\, by Bo-Wei Qin et. al.\, Nature Communications\, 2021. \nZoom : https://us06web.zoom.us/j/99567630778?pwd=N2ZrUWtqZzJ0YURVTzlZT3JJR3FUQT09 \nAbstract  \nBiorhythm including neuron firing and protein-mRNA interaction are fundamental activities with diffusive effect. Their well-balanced spatiotemporal dynamics are beneficial for healthy sustainability. Therefore\, calibrating both anomalous frequency and amplitude of biorhythm prevents physiological dysfunctions or diseases. However\, many works were devoted to modulate frequency exclusively whereas amplitude is usually ignored\, although both quantities are equally significant for coordinating biological functions and outputs. Especially\, a feasible method coordinating the two quantities concurrently and precisely is still lacking. Here\, for the first time\, we propose a universal approach to design a frequency-amplitude coordinator rigorously via dynamical systems tools. We consider both spatial and temporal information. With a single well-designed coordinator\, they can be calibrated to desired levels simultaneously and precisely. The practical usefulness and efficacy of our method are demonstrated in representative neuronal and gene regulatory models. We further reveal its fundamental mechanism and optimal energy consumption providing inspiration for biorhythm regulation in future.
URL:https://www.ibs.re.kr/bimag/event/eui-min-jeong-a-frequency-amplitude-coordinator-and-its-optimal-energy-consumption-for-biological-oscillators/
LOCATION:Daejeon
CATEGORIES:Journal Club
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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