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X-ORIGINAL-URL:https://www.ibs.re.kr/bimag
X-WR-CALDESC:Events for Biomedical Mathematics Group
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TZID:Asia/Seoul
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TZOFFSETFROM:+0900
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DTSTART:20200101T000000
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BEGIN:VEVENT
DTSTART;TZID=Asia/Seoul:20211008T140000
DTEND;TZID=Asia/Seoul:20211008T150000
DTSTAMP:20260427T105242
CREATED:20211007T190000Z
LAST-MODIFIED:20211006T081805Z
UID:4912-1633701600-1633705200@www.ibs.re.kr
SUMMARY:Balanced truncation for model reduction of biological oscillators
DESCRIPTION:We will discuss about “Balanced truncation for model reduction of biological oscillators”\, Padoan et al.\, Biological Cybernetics\, 2021 \nModel reduction is a central problem in mathematical biology. Reduced order models enable modeling of a biological system at different levels of complexity and the quantitative analysis of its properties\, like sensitivity to parameter variations and resilience to exogenous perturbations. However\, available model reduction methods often fail to capture a diverse range of nonlinear behaviors observed in biology\, such as multistability and limit cycle oscillations. The paper addresses this need using differential analysis. This approach leads to a nonlinear enhancement of classical balanced truncation for biological systems whose behavior is not restricted to the stability of a single equilibrium. Numerical results suggest that the proposed framework may be relevant to the approximation of classical models of biological systems.
URL:https://www.ibs.re.kr/bimag/event/2021-10-8/
LOCATION:B378 Seminar room\, IBS\, 55 Expo-ro Yuseong-gu\, Daejeon\, 34126\, Korea\, Republic of
CATEGORIES:Journal Club
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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