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X-WR-CALDESC:Events for Biomedical Mathematics Group
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DTSTART:20220101T000000
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DTSTART;TZID=Asia/Seoul:20230728T100000
DTEND;TZID=Asia/Seoul:20230728T110000
DTSTAMP:20260426T031541
CREATED:20230619T074840Z
LAST-MODIFIED:20230726T042649Z
UID:7948-1690538400-1690542000@www.ibs.re.kr
SUMMARY:Yun Min Song\, The singularity response reveals entrainment properties of the plant circadian clock
DESCRIPTION:We will discuss about “The singularity response reveals entrainment properties of the plant circadian clock”\, Masuda\, Kosaku\, et al.\, Nature Communications 12.1 (2021): 864. \nAbstract \n\n\n\n\n\n\nCircadian clocks allow organisms to synchronize their physiological processes to diurnal variations. A phase response curve allows researchers to understand clock entrainment by revealing how signals adjust clock genes differently according to the phase in which they are applied. Comprehensively investigating these curves is difficult\, however\, because of the cost of measuring them experimentally. Here we demonstrate that fundamental properties of the curve are recoverable from the singularity response\, which is easily measured by applying a single stimulus to a cellular network in a desynchronized state (i.e. singularity). We show that the singularity response of Arabidopsis to light/dark and temperature stimuli depends on the properties of the phase response curve for these stimuli. The measured singularity responses not only allow the curves to be precisely reconstructed but also reveal organ-specific properties of the plant circadian clock. The method is not only simple and accurate\, but also general and applicable to other coupled oscillator systems as long as the oscillators can be desynchronized. This simplified method may allow the entrainment properties of the circadian clock of both plants and other species in nature.
URL:https://www.ibs.re.kr/bimag/event/2023-07-28/
LOCATION:B232 Seminar Room\, IBS\, 55 Expo-ro Yuseong-gu\, Daejeon\, Daejeon\, 34126\, Korea\, Republic of
CATEGORIES:Journal Club
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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