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X-ORIGINAL-URL:https://www.ibs.re.kr/bimag
X-WR-CALDESC:Events for Biomedical Mathematics Group
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TZID:Asia/Seoul
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TZOFFSETFROM:+0900
TZOFFSETTO:+0900
TZNAME:KST
DTSTART:20230101T000000
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BEGIN:VEVENT
DTSTART;TZID=Asia/Seoul:20240109T100000
DTEND;TZID=Asia/Seoul:20240109T110000
DTSTAMP:20260505T125122
CREATED:20240103T102249Z
LAST-MODIFIED:20240107T033247Z
UID:9021-1704794400-1704798000@www.ibs.re.kr
SUMMARY:Hyung Jin Choi\, A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
DESCRIPTION:Abstract: Physiological needs evoke motivational drives to produce natural behaviours for survival. However\, the temporally intertwined dynamics of need and motivation have made it challenging to differentiate these two components in previous experimental paradigms. Based on classic homeostatic theories\, we established a normative framework to derive computational models of neural activity and behaviours for need-encoding and motivation-encoding neurons during events that induce predicted gain or loss. We further developed simple and intuitive experimental paradigms that enabled us to distinguish the distinct roles of subpopulations of neurons in the hypothalamus. Our results show that AgRP neurons and LHLepR neurons are consistent with need and motivation\, respectively. Our study provides a parsimonious understanding of how distinct hypothalamic neurons separately encode need and motivation to produce adaptive behaviours for maintaining homeostasis.\n\nZOOM ID: 997 8258 4700 (Biomedical Mathematics Online Colloquium)\, (pw: 1234)
URL:https://www.ibs.re.kr/bimag/event/hyung-jin-choi-a-normative-framework-dissociates-need-and-motivation-in-hypothalamic-neurons-3/
LOCATION:B232 Seminar Room\, IBS\, 55 Expo-ro Yuseong-gu\, Daejeon\, Daejeon\, 34126\, Korea\, Republic of
CATEGORIES:Biomedical Mathematics Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.ibs.re.kr/bimag/cms/wp-content/uploads/2024/01/최형진-사진-HAHN1836-실험가운-해부학-1-1-1-e1704595806914.jpg
ORGANIZER;CN="Jae Kyoung Kim":MAILTO:jaekkim@kaist.ac.kr
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